LFF Convenes Leading Experts to Discuss Strategies to Accelerate Alzheimer’s Research

September 15, 2022

MARTHA’S VINEYARD, Mass. — In September 2022, LFF organized its first-ever roundtable meeting in Martha’s Vineyard, Mass., entitled “Re-thinking the Initial Mechanistic Triggers of Alzheimer’s Disease: Opportunities, Obstacles, and Paths Forward.”

We convened a select group of grantees representing a variety of scientific disciplines, expertise, and career stages from around the country.

The goal of the meeting was to stimulate a robust, “outside the box” discussion of various hypotheses underlying the root causes of Alzheimer’s disease (AD) and to determine opportunities for impact in AD research.

Even though the Alzheimer’s research field has been pushing forward with a variety of new therapeutics, we have not yet seen meaningful clinical outcomes. The group outlined strategies to identify downstream common mechanisms underlying an inflection point from “normal” to “disease” where we could intervene.  

While research into the cause of AD is critical, the cause is not necessarily the cure, and understanding targets involved in progression of the disease may be equally if not more important.

About the Carol and Gene Ludwig Family Foundation
Established in 2002, the Carol and Gene Ludwig Family Foundation (LFF) invests in organizations through strategic grantmaking that accelerate medical and scientific discovery, enable access to educational and economic opportunity for young people, and enriches and strengthens the communities where the founders live and work.

Carol Ludwig is a neurologist and the president of the Carol and Gene Ludwig Family Foundation. She serves on the board of KIPP-DC and on the Council of Medical Advisors for the Columbia University Irvine Medical Center, where she is part of the Neurology Advisory and Medical Education Committees and the Precision Medicine Council. A summa cum laude graduate of Bryn Mawr College and The Columbia University Vagelos College of Physicians and Surgeons, she was a Commissioned Officer in the U.S. Public Health Service. She has worked at the National Institutes of Health, The Armed Forces Institute of Pathology, and as a faculty member at the George Washington University Medical Center.

Gene Ludwig is founder of the Promontory family of companies and Canapi LLC, a financial technology venture fund. He is the CEO of Promontory MortgagePath, a technology-based mortgage fulfillment and solutions company, chairman of Promontory Financial Group, and founder and chairman of the Ludwig Institute for Shared Economic Prosperity (LISEP), an organization dedicated to improving the economic well-being of lower- and middle-income Amerians. Ludwig is the former vice chairman and senior control officer of Bankers Trust New York Corp., and served as the U.S. Comptroller of the Currency from 1993 to 1998.